مشروع البحث: Variation of hematological parameters in anemic pregnant women with or without periodontitis in Gharyan city
| dc.contributor.advisor | د.جبريل مسعود جبريل | |
| dc.date.accessioned | 2026-04-15T09:28:47Z | |
| dc.date.available | 2026-04-15T09:28:47Z | |
| dc.description | Introduction: Anemia during pregnancy is a significant public health concern that adversely affects maternal and fetal outcomes. Periodontitis, a chronic inflammatory oral disease, has been suggested to exacerbate systemic inflammation and hematological imbalances. This study aims to investigate the variations in hematological parameters among anemic pregnant women with and without periodontitis in Gharyan City, exploring the potential impact of periodontal disease on systemic inflammation and anemia severity during pregnancy. Methodology: A cross-sectional study was conducted involving 112 anemic pregnant women attending antenatal clinics in Gharyan City. Participants were divided into two groups: anemic pregnant women without periodontitis (n=50) and anemic pregnant women with clinically diagnosed periodontitis (n=62). Comprehensive periodontal examinations, including plaque index, gingival index, probing pocket depth, bleeding on probing, and gum discoloration assessments, were performed. Hematological parameters, including hemoglobin (Hb), red blood cell count (RBC), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), platelet count (PLT), white blood cell count (WBC), and serum ferritin, were measured. Statistical analyses included descriptive statistics, Pearson correlation, and ANOVA tests to compare and correlate variables within and between groups. Results: Both groups were similar in age and gestational distribution. The periodontitis group exhibited significantly higher plaque accumulation, gingival inflammation, bleeding on probing, and gum redness. Hematological analysis showed that the periodontitis group had slightly lower Hb and HCT levels, higher PLT and WBC counts, and lower ferritin levels compared to the anemic-only group. Significant correlations between Hb and hematological indices, including a negative correlation with PLT, were observed predominantly in the periodontitis group. ANOVA results indicated more uniform hematological parameters within the periodontitis group, whereas the anemic-only group showed greater variability in Hb and HCT. Discussion: The findings suggest that periodontitis contributes to a systemic inflammatory state that exacerbates anemia severity and alters hematological parameters in pregnant women. The increased platelet and white blood cell counts reflect an inflammatory response, while lower ferritin levels may indicate impaired iron metabolism due to chronic inflammation. The more consistent hematological profile in the periodontitis group points to periodontal disease as a systemic equalizer, intensifying the inflammatory burden in anemia during pregnancy. Conclusion: Periodontitis significantly impacts the hematological health of anemic pregnant women by worsening anemia and inducing systemic inflammation. Integrating periodontal screening and treatment into prenatal care is recommended to mitigate these effects and improve maternal and fetal health outcomes. | |
| dc.description.abstract | Introduction: Anemia during pregnancy is a significant public health concern that adversely affects maternal and fetal outcomes. Periodontitis, a chronic inflammatory oral disease, has been suggested to exacerbate systemic inflammation and hematological imbalances. This study aims to investigate the variations in hematological parameters among anemic pregnant women with and without periodontitis in Gharyan City, exploring the potential impact of periodontal disease on systemic inflammation and anemia severity during pregnancy. Methodology: A cross-sectional study was conducted involving 112 anemic pregnant women attending antenatal clinics in Gharyan City. Participants were divided into two groups: anemic pregnant women without periodontitis (n=50) and anemic pregnant women with clinically diagnosed periodontitis (n=62). Comprehensive periodontal examinations, including plaque index, gingival index, probing pocket depth, bleeding on probing, and gum discoloration assessments, were performed. Hematological parameters, including hemoglobin (Hb), red blood cell count (RBC), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), platelet count (PLT), white blood cell count (WBC), and serum ferritin, were measured. Statistical analyses included descriptive statistics, Pearson correlation, and ANOVA tests to compare and correlate variables within and between groups. Results: Both groups were similar in age and gestational distribution. The periodontitis group exhibited significantly higher plaque accumulation, gingival inflammation, bleeding on probing, and gum redness. Hematological analysis showed that the periodontitis group had slightly lower Hb and HCT levels, higher PLT and WBC counts, and lower ferritin levels compared to the anemic-only group. Significant correlations between Hb and hematological indices, including a negative correlation with PLT, were observed predominantly in the periodontitis group. ANOVA results indicated more uniform hematological parameters within the periodontitis group, whereas the anemic-only group showed greater variability in Hb and HCT. Discussion: The findings suggest that periodontitis contributes to a systemic inflammatory state that exacerbates anemia severity and alters hematological parameters in pregnant women. The increased platelet and white blood cell counts reflect an inflammatory response, while lower ferritin levels may indicate impaired iron metabolism due to chronic inflammation. The more consistent hematological profile in the periodontitis group points to periodontal disease as a systemic equalizer, intensifying the inflammatory burden in anemia during pregnancy. Conclusion: Periodontitis significantly impacts the hematological health of anemic pregnant women by worsening anemia and inducing systemic inflammation. Integrating periodontal screening and treatment into prenatal care is recommended to mitigate these effects and improve maternal and fetal health outcomes. | |
| dc.identifier | 7-1 | |
| dc.identifier.uri | https://dspace.academy.edu.ly/handle/123456789/1948 | |
| dc.subject | Variation of hematological parameters in anemic pregnant women with or without periodontitis in Gharyan city | |
| dc.title | Variation of hematological parameters in anemic pregnant women with or without periodontitis in Gharyan city | |
| dspace.entity.type | Project | |
| project.endDate | 2025 | |
| project.funder.name | علوم حياة | |
| project.investigator | صفاء البهلول البكاي | |
| project.startDate | 2024 |
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