Dr. Soner BİLEN2024-12-092024-12-09https://dspace.academy.edu.ly/handle/123456789/650However, food conversion ratio (FCR) of experimental groups were significantly reduced compared to the control. These results indicated that the supplementation of methanolic extract of P. terebinthus to the diet of O. mykiss is beneficial because it increases the digestive enzyme secretion, antioxidant enzyme activities, nonspecific immune responses and growth performance parameters.ABSTRACT In this study the effect of the methanolic extract of meningy, Pistacia terebinthus (PT), fruits supplemented diet on digestive enzymes activity, antioxidant enzymes activitiy, non-specific immunty, heamatological parameters and growth performance were evalated in juvenile rainbow trout, Onchoryhnhus mykiss. A total number 480 fish with initial mean body weight, 15.77±0.13g were divided into four main groups in triplicate (twelve tank, 40 fish per tank). Fish fed a diet containing three doses of PT extract [PT 0,(Control) PT 0.5%, PT 0.1% and PT 1% / kg diet] individually for 63 days. The samples were collected every 21 days. The digestive enzyme results indecated that pepsin and lipase activities were significantly increased in all treated groups. In addition, trypsin acitivity in PT 0.1% and PT 1% groups were significantly improved. While, amylase enzyme activity was significantly increased in PT 0.5% and PT 1% compared to the control. Also, significantly improvement in hepatic superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glucose-6-phosphate dehydrogenase (G6PDH) activities in all treatment groups and in all sampling times except in PT 0.5%. At the same time hepatic CAT activity was(YO) kontrole göre azalma söz konusu olmuştur (P<0,05). Bu sonuçlar P. terebinthus metanolik ekstraktının sindirim enzimlerinin salgılanmasını, antioksidan enzim