Dr. Ali Rownaghi, Advisor2025-12-162025-12-16https://dspace.academy.edu.ly/handle/123456789/1850Many biological systems that utilize organic active sites to catalyze reactions under mild conditions invoke cooperative catalytic pathways, whereby two or more active sites work together to activate the reactant(s). The use of cooperative (bifunctional) catalysts and continuous flow chemistry (a reaction within the narrow channels of a micro‐ or microfluidic reactor) are commonplace in sustainable chemical transformation and attract a great deal of interest with respect to economic and environmentally-sustainable production of fine chemicals, pharmaceuticals, and agrochemicals, water treatment, as well as upgrading of biomass feedstocks.The HFs-IPA were proved to be successful being the surface modification to load various catalytic efficiency composite on the inner wall of the fiber shell and employed into various organic synthesis reactions. Meanwhile, the different doping of the halogens not only help to improve the mechanical strength of the HFs-IPA catalysts but also providing various active sites to help increase the cooperation of the -OH and -NH sites when working as the multifunctional organocatalysts. Besides, depend on the BET surface area and pore size measurement analysis, the polymeric hollow fiber appeared having highly porous and surface to volume ratio, which can improve the contact between the reactant residential time with the catalytic area, provide excellent mass transfer properties, and lower resistance to flow during the pass-thought the shell of the hollow fiber inner-wall.PHARMACEUTICAL COMPOUNDS OVER INTELLIGENTCONTINUOUS-FLOW SYNTHESIS OF FINE CHEMICALS AND PHARMACEUTICAL COMPOUNDS OVER INTELLIGENT ORGANOCATALYSTS WITH BIFUNCTIONAL REACTIVITY