مشروع البحث: Risk Factors for Urinary Tract Infections among Adult Type 2 Diabetic Patients in Gharyan, Libya
| dc.contributor.advisor | د.مصطفي عمران السائح | |
| dc.date.accessioned | 2026-05-13T07:13:56Z | |
| dc.date.available | 2026-05-13T07:13:56Z | |
| dc.description | This study aimed to evaluate the risk factors independently associated with UTIs among adult T2DM patients and compare them with non-diabetic patients in Gharyan, Libya. The study was conducted at Gharyan Medical Center from February to October 2025. A total of 100 adult T2DM patients attending diabetic clinics and 80 adult non-diabetic patients (controls), all with confirmed UTIs, were enrolled. Demographic and clinical data were collected using a structured questionnaire, medical records review, and urine culture analysis for a sub-sample of 50 T2DM patients. Data were analyzed using SPSS version 20, and the Chi-square test was used to determine statistically significant associations with UTI recurrence rates. UTIs were significantly higher among T2DM patients (p = 0.02), with 28% presenting as asymptomatic bacteriuria (ASB) compared to 6.2% in the non-diabetic group. Key risk factors among diabetic patients included poor glycemic control (HbA1c > 7.5%), diabetes duration exceeding ten years, and a high comorbidity index, all strongly associated with increased UTI recurrence (p < 0.01). Female gender, advanced age (>60 years), history of catheterization, obesity (BMI > 30), and lack of physical activity were associated with increased UTI rates in both groups, though without statistically significant differences between them. Recurrent UTIs were more frequent in diabetic patients, with females showing the highest incidence. Notably, T2DM patients on SGLT2 inhibitors had significantly higher UTI rates compared to metformin users (p < 0.01). Escherichia coli was the predominant uropathogen (64.0%), followed by Klebsiella pneumoniae (14.0%), Pseudomonas spp. (10.0%), Enterococcus spp. (8.0%), and Proteus vulgaris (4.0%). This study demonstrates that T2DM patients in Gharyan have significantly higher UTI recurrence rates, with a substantial proportion presenting as asymptomatic bacteriuria. Key risk factors include poor glycemic control, prolonged diabetes duration, comorbidities, and SGLT2 inhibitor use. These findings emphasize the need for regular UTI screening in high-risk populations, careful assessment of diabetes medication risks, and enhanced health awareness programs for effective prevention and management of UTIs among diabetic patients in Gharyan. Keywords: Urinary tract infection (UTI); type 2 diabetes mellitus (T2DM); risk factors; asymptomatic bacteriuria; SGLT2 inhibitors; Libya; Gharyan. | |
| dc.description.abstract | This study aimed to evaluate the risk factors independently associated with UTIs among adult T2DM patients and compare them with non-diabetic patients in Gharyan, Libya. The study was conducted at Gharyan Medical Center from February to October 2025. A total of 100 adult T2DM patients attending diabetic clinics and 80 adult non-diabetic patients (controls), all with confirmed UTIs, were enrolled. Demographic and clinical data were collected using a structured questionnaire, medical records review, and urine culture analysis for a sub-sample of 50 T2DM patients. Data were analyzed using SPSS version 20, and the Chi-square test was used to determine statistically significant associations with UTI recurrence rates. UTIs were significantly higher among T2DM patients (p = 0.02), with 28% presenting as asymptomatic bacteriuria (ASB) compared to 6.2% in the non-diabetic group. Key risk factors among diabetic patients included poor glycemic control (HbA1c > 7.5%), diabetes duration exceeding ten years, and a high comorbidity index, all strongly associated with increased UTI recurrence (p < 0.01). Female gender, advanced age (>60 years), history of catheterization, obesity (BMI > 30), and lack of physical activity were associated with increased UTI rates in both groups, though without statistically significant differences between them. Recurrent UTIs were more frequent in diabetic patients, with females showing the highest incidence. Notably, T2DM patients on SGLT2 inhibitors had significantly higher UTI rates compared to metformin users (p < 0.01). Escherichia coli was the predominant uropathogen (64.0%), followed by Klebsiella pneumoniae (14.0%), Pseudomonas spp. (10.0%), Enterococcus spp. (8.0%), and Proteus vulgaris (4.0%). This study demonstrates that T2DM patients in Gharyan have significantly higher UTI recurrence rates, with a substantial proportion presenting as asymptomatic bacteriuria. Key risk factors include poor glycemic control, prolonged diabetes duration, comorbidities, and SGLT2 inhibitor use. These findings emphasize the need for regular UTI screening in high-risk populations, careful assessment of diabetes medication risks, and enhanced health awareness programs for effective prevention and management of UTIs among diabetic patients in Gharyan. Keywords: Urinary tract infection (UTI); type 2 diabetes mellitus (T2DM); risk factors; asymptomatic bacteriuria; SGLT2 inhibitors; Libya; Gharyan. | |
| dc.identifier | 10-1 | |
| dc.identifier.uri | https://dspace.academy.edu.ly/handle/123456789/2046 | |
| dc.subject | Risk Factors for Urinary Tract Infections among Adult Type 2 Diabetic Patients in Gharyan, Libya | |
| dc.title | Risk Factors for Urinary Tract Infections among Adult Type 2 Diabetic Patients in Gharyan, Libya | |
| dspace.entity.type | Project | |
| project.endDate | 2026 | |
| project.funder.name | علوم حياة | |
| project.investigator | نادية فتحي رمضان الزوالي | |
| project.startDate | 2025 |
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