مشروع البحث: إستخدام معدل الكرياتينين/ ألبيومين كعامل خطر للدلالة على الإعتلال الكبيبي المبكرعند مرضى السكر من النمط الثاني في طرابلس, ليبيا.
| dc.contributor.advisor | عبد الحفيظ على الشيباني | |
| dc.date.accessioned | 2025-03-23T11:19:15Z | |
| dc.date.available | 2025-03-23T11:19:15Z | |
| dc.description | Background: Nephropathy is considered a major causative for illness and death among diabetes mellitus type 2 patients. The diabetic nephropathy has become the main cause of chronic kidney disease, and progress to kidney failure that requires lifelong dialysis or a kidney transplant. The progression of diabetic nephropathy from the appearance of proteinuria to end-stage renal disease (ESRD) accounts for about 20-40% of patients with diabetes mellitus type 2. With scarce in data about the prevalence of diabetic nephropathy among Libyan patients with diabetes mellitus type 2. Objectives: This study aimed to evaluate the prevalence of diabetic nephropathy in an early stage, and to determine the related risk factors among Libyan type 2 diabetic patients attending diabetic Out Patient Department clinic at Tripoli University Hospital. Subjects and Methods: A cross-sectional prospective study was conducted with a sample of 125 eligible diabetes mellitus type 2 patients aged 22-80 years, recruited via attendance to diabetes Out Patient Department clinic at Tripoli University Hospital , Tripoli, Libya. A well-designed questionnaire was used to gather demographic characteristics, clinical data, and laboratory assessment of HbA1c, serum creatinine, BUN, serum cholesterol, and triglyceride. The early diabetic nephropathy was defined as Albumin/ Creatinine Ratio 30mg/g and above. The Results: The majority of our recruited subjects (92/125, 73.6%) were females, and the mean age of the patients was 54.72 years, the mean duration of diabetes in the study population was 9.47 years, and the mean glycosylated hemoglobin (HbA1c) for our study group was 7.95% with about 70% of the patients having HbA1c over 7%. Proteinuria was found in 27 of the participants. The prevalence of diabetic nephropathy among our study group was 21.6%. Furthermore, the statistical analysis revealed that being a smoking patient (p=0.002), and having uncontrolled glycosylated hemoglobin (HbA1c) (p=0.003) were significantly associated with the presence of proteinuria | |
| dc.description.abstract | Background: Nephropathy is considered a major causative for illness and death among diabetes mellitus type 2 patients. The diabetic nephropathy has become the main cause of chronic kidney disease, and progress to kidney failure that requires lifelong dialysis or a kidney transplant. The progression of diabetic nephropathy from the appearance of proteinuria to end-stage renal disease (ESRD) accounts for about 20-40% of patients with diabetes mellitus type 2. With scarce in data about the prevalence of diabetic nephropathy among Libyan patients with diabetes mellitus type 2. Objectives: This study aimed to evaluate the prevalence of diabetic nephropathy in an early stage, and to determine the related risk factors among Libyan type 2 diabetic patients attending diabetic Out Patient Department clinic at Tripoli University Hospital. Subjects and Methods: A cross-sectional prospective study was conducted with a sample of 125 eligible diabetes mellitus type 2 patients aged 22-80 years, recruited via attendance to diabetes Out Patient Department clinic at Tripoli University Hospital , Tripoli, Libya. A well-designed questionnaire was used to gather demographic characteristics, clinical data, and laboratory assessment of HbA1c, serum creatinine, BUN, serum cholesterol, and triglyceride. The early diabetic nephropathy was defined as Albumin/ Creatinine Ratio 30mg/g and above. The Results: The majority of our recruited subjects (92/125, 73.6%) were females, and the mean age of the patients was 54.72 years, the mean duration of diabetes in the study population was 9.47 years, and the mean glycosylated hemoglobin (HbA1c) for our study group was 7.95% with about 70% of the patients having HbA1c over 7%. Proteinuria was found in 27 of the participants. The prevalence of diabetic nephropathy among our study group was 21.6%. Furthermore, the statistical analysis revealed that being a smoking patient (p=0.002), and having uncontrolled glycosylated hemoglobin (HbA1c) (p=0.003) were significantly associated with the presence of proteinuria | |
| dc.identifier | 7144 | |
| dc.identifier.uri | https://dspace.academy.edu.ly/handle/123456789/1590 | |
| dc.subject | إستخدام معدل الكرياتينين/ ألبيومين | |
| dc.title | إستخدام معدل الكرياتينين/ ألبيومين كعامل خطر للدلالة على الإعتلال الكبيبي المبكرعند مرضى السكر من النمط الثاني في طرابلس, ليبيا. | |
| dspace.entity.type | Project | |
| project.endDate | 2019 | |
| project.funder.name | علم الحيوان | |
| project.investigator | سعاد محمد الصوم | |
| project.startDate | 2018 | |
| relation.isOrgUnitOfProject | ffbfb1aa-e8d9-4fc6-9a55-a1ff8f1ed009 | |
| relation.isOrgUnitOfProject.latestForDiscovery | ffbfb1aa-e8d9-4fc6-9a55-a1ff8f1ed009 |