مشروع البحث: العلاقة بين مستويات الحموضة في اللعاب وتسوس الاسنان لدى مرضى السكري من النوع الثاني: دراسة في بلدية الخمس Correlation Between Salivary PH Levels and Dental Caries in Type 2 Diabetic Patients: A Study in Alkhoms Municipality
| dc.contributor.advisor | عطية رمضان الكيلاني | |
| dc.date.accessioned | 2026-05-20T08:12:14Z | |
| dc.date.available | 2026-05-20T08:12:14Z | |
| dc.description | Type 2 Diabetes Mellitus (T2DM) represents one of the most significant global health challenges of the twenty-first century, affecting both systemic and oral health. Alterations in salivary composition among diabetic individuals may predispose them to higher rates of dental caries, yet this relationship remains underexplored in many regions, including North Africa. This research aimed to investigate the correlation between salivary PH levels and dental caries among patients with T2DM in Alkhoms Municipality, Libya, and to determine the influence of glycemic control and oral hygiene on this association. A cross-sectional study was conducted involving 289 adult diabetic participants aged 30–45 years. Data was collected between April and July 2025. Unstimulated saliva samples were analyzed for PH using a calibrated digital PH meter. Dental caries was assessed using the Decayed, Missing, and Filled Teeth (DMFT) index. Glycemic control was evaluated by HbA1c levels, and oral hygiene behaviors were recorded through structured interviews. Statistical analyses included correlation tests, ANOVA, and multivariable regression models to identify independent predictors of caries risk. The results of this showed that mean salivary PH was 6.08 ± 0.53. A strong inverse correlation was observed between PH and DMFT (r = –0.897, p < 0.001). HbA1c showed a significant negative relationship with PH (r = –0.28, p < 0.001) and a positive association with DMFT (r = 0.21, p = 0.002). Poor oral hygiene further intensified caries occurrence. Regression analyses identified salivary PH, HbA1c, and oral hygiene as the most influential independent determinants of caries. The findings confirm that reduced salivary PH mediates the link between poor glycemic control and dental decay. Incorporating salivary testing into diabetic care could provide a simple, non-invasive, and cost-effective strategy for early detection and prevention of oral complications in diabetic populations. | |
| dc.description.abstract | Type 2 Diabetes Mellitus (T2DM) represents one of the most significant global health challenges of the twenty-first century, affecting both systemic and oral health. Alterations in salivary composition among diabetic individuals may predispose them to higher rates of dental caries, yet this relationship remains underexplored in many regions, including North Africa. This research aimed to investigate the correlation between salivary PH levels and dental caries among patients with T2DM in Alkhoms Municipality, Libya, and to determine the influence of glycemic control and oral hygiene on this association. A cross-sectional study was conducted involving 289 adult diabetic participants aged 30–45 years. Data was collected between April and July 2025. Unstimulated saliva samples were analyzed for PH using a calibrated digital PH meter. Dental caries was assessed using the Decayed, Missing, and Filled Teeth (DMFT) index. Glycemic control was evaluated by HbA1c levels, and oral hygiene behaviors were recorded through structured interviews. Statistical analyses included correlation tests, ANOVA, and multivariable regression models to identify independent predictors of caries risk. The results of this showed that mean salivary PH was 6.08 ± 0.53. A strong inverse correlation was observed between PH and DMFT (r = –0.897, p < 0.001). HbA1c showed a significant negative relationship with PH (r = –0.28, p < 0.001) and a positive association with DMFT (r = 0.21, p = 0.002). Poor oral hygiene further intensified caries occurrence. Regression analyses identified salivary PH, HbA1c, and oral hygiene as the most influential independent determinants of caries. The findings confirm that reduced salivary PH mediates the link between poor glycemic control and dental decay. Incorporating salivary testing into diabetic care could provide a simple, non-invasive, and cost-effective strategy for early detection and prevention of oral complications in diabetic populations. | |
| dc.identifier | 3-5 | |
| dc.identifier.uri | https://dspace.academy.edu.ly/handle/123456789/2077 | |
| dc.subject | علوم حياة | |
| dc.title | العلاقة بين مستويات الحموضة في اللعاب وتسوس الاسنان لدى مرضى السكري من النوع الثاني: دراسة في بلدية الخمس Correlation Between Salivary PH Levels and Dental Caries in Type 2 Diabetic Patients: A Study in Alkhoms Municipality | |
| dspace.entity.type | Project | |
| project.endDate | 2025 | |
| project.funder.name | علوم اساسية | |
| project.investigator | هيثم ميلاد أنويجي | |
| project.startDate | 2024 |