مشروع البحث: In silico study of pyrazino {2,3-g}quinoxaline-5,10-diones as potential anticancer drugs
| dc.contributor.advisor | د.محمد عثمان محمد أحمد الفقى | |
| dc.date.accessioned | 2026-06-25T07:07:16Z | |
| dc.date.available | 2026-06-25T07:07:16Z | |
| dc.description | Computer aided drug design techniques could be used to propose rational sequence of steps to uncover potentaily active agents of quinone containing anticancer agents with flanking quinoxaline rings. Thus establishing a plausible methodology for drug discovery process that could be adapted for the discovery of other therapeutic agent used to combat any diseases including cancer . the basic assumption in this work is that there is a strong correlation between cytotoxicity and calculated baseline toxicity. | |
| dc.description.abstract | Cancer is a complex genetic disease that is caused primarily by environmental factors. The cancer-causing agents (carcinogens) can be present in food and water, in the air, and in chemicals and sunlight that people are exposed to. Since epithelial cells cover the skin, line the respiratory and alimentary tracts, and metabolize ingested carcinogens, it is not surprising that over 90% of cancers occur in epithelia. The causes of serious ill-health in the world are changing. Infection as a major cause is giving way to non communicable diseases such as cardiovascular disease and cancer. In 1996 there were 10 million new cancer cases worldwide and six million deaths attributed to cancer. In 2020 there are predicted to be 20 million new cases and 12 million deaths. | |
| dc.identifier | 5916 | |
| dc.identifier.uri | https://dspace.academy.edu.ly/handle/123456789/2347 | |
| dc.subject | Potential Anticancer Drugs | |
| dc.title | In silico study of pyrazino {2,3-g}quinoxaline-5,10-diones as potential anticancer drugs | |
| dspace.entity.type | Project | |
| project.endDate | 2015 | |
| project.funder.name | علوم الحياة | |
| project.investigator | محمد عمر الجابو | |
| project.startDate | 2014 |