مشروع البحث: Bacterial pathogens causing ventilator associated pneumonia in neonates at Tripoli University Hospital
| dc.contributor.advisor | Dr. Raja Moftah Moman | |
| dc.date.accessioned | 2024-12-03T13:36:18Z | |
| dc.date.available | 2024-12-03T13:36:18Z | |
| dc.description | Methods and patients: A prospective hospital-based observation study included 915 neonates admitted to the NICUs at TUH over 25 months. Ninety neonates who required mechanical ventilation for at least 48 hours were included in the study. The clinical pulmonary infection score was used, which takes into consideration data from radiography, microbiology, and clinical laboratories. The microbiological flora was assessed by culturing and testing endotracheal aspirate (ETA) samples for sensitivity. Results: The total number of neonates admitted to the NICUs during the study pe915 newborns. Ninety neonates required mechanical ventilation for at least 2 days. In relation to gender, 55.6% were males an riod was d 44.4% were females. Bacterial strains isolated included 112 strains of bacteria, of which 74 (66%) were pathogenic. Gram-negative bacteria contributed to 79.5%. The most common organisms were multidrug-resistant (MDR) Acinetobacter baumannii followed by Klebsiella pneumoniae, and Pseudomonas aeruginosa. The majority of them were resistant, including meropenem, but maximum sensitivity was observed for amikacin in these isolates. Conclusions: In conclusion, authorities should focus more on NICUs in hospitals to improve the health of hospitalized neonates and reduce complications, length of stay, and expenses because VAP is a serious and severe infection. Additionally, future studies ought to look into the reasons for incompetence | |
| dc.description.abstract | ABSTACT Introduction: Ventilator-associated pneumonia (VAP) is defined as pneumonia that occurs 2 days following endotracheal intubation or after that. It is the second most common infection encountered among intubated patients and the second most related hospital-acquired infection (HAI) among pediatrics and neonates in intensive care units (ICUs). Additionally, it is one of the most common healthcare-associated infections among ventilated neonates. VAP incidence shows wide inconsistency between countries. Aim: To identify bacterial pathogens that cause VAP in newborns and to assess the antibiotic susceptibility patterns of isolated bacteria at Tripoli University Hospital (TUH) between December 2020 and December 2022. Methods and patients: A prospective hospital-based observation study included 915 neonates admitted to the NICUs at TUH over 25 months. Ninety neonates who required mechanical ventilation for at least 48 hours were included in the study. The clinical pulmonary infection score was used, which takes into consideration data from radiography, microbiology, and clinical laboratories. The microbiological flora was assessed by culturing and testing endotracheal aspirate (ETA) samples for sensitivity | |
| dc.identifier | 24472 | |
| dc.identifier.uri | https://dspace.academy.edu.ly/handle/123456789/484 | |
| dc.subject | Conclusions: In conclusion, authorities should focus more | |
| dc.title | Bacterial pathogens causing ventilator associated pneumonia in neonates at Tripoli University Hospital | |
| dspace.entity.type | Project | |
| project.endDate | 2024 | |
| project.funder.name | Division of Microbiology | |
| project.investigator | Entesar Maatouq Aldaeri | |
| project.startDate | 2023 |