مشروع البحث: Genoprotective effect of aspirin and ibuprofen in human lymphocyte cells
تحميل...
المساهمين
الممولين
رقم التعريف
766
الباحث
أسامة محمد محمد دلله
الوصف
Both aspirin and ibuprofen caused a reduction in DNA damage and micronucleus formation. Aspirin, both forms, showed a reduction in DNA damage in the Comet and micronucleus assays. Ibuprofen both forms, by contrast, showed a statistically significant reduction in micronucleus frequency in the micronucleus assay, while its preventative effect with the Comet assay was weak or insignificant. NPs of both agents were more effective than bulk sizes. Using the Comet repair assay, aspirin and ibuprofen nano form catalysed DNA repair to a greater extent than their bulk forms. Also, both sizes showed better repair with NSAIDs compared to samples repaired without NSAIDs.
الكلمات الدالة
Genoprotective effect of aspirin